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Brain Tumors & The Usage Of A Two-Drug Tandem

By Robbie Sutter


Brain tumors are going to be given a great amount of focus as far as the usage of certain drugs is concerned. Some of these drugs may be more useful than others but the truth of the matter is that they can come from many different sources. While it's clear that there are those which are entirely unique, there are just as many - if not more - that have been put to use in order to treat entirely different conditions in the past. Is it possible, then, that a two-drug combination can help matters in this particular field?

According to an article on YottaFire, it appears as though this is the case, as a new combination of drugs has been put to use in order to help slow down the growth rate of brain tumors. The study was conducted through a group of mice in order to see how well their survival rates have become. Fortunately, results were positive, as their levels of survival were made even greater. This is just the start as to why such a story is worthy of the attention of organizations such as Voices against Brain Cancer.

Researchers at the Dana-Farber Cancer Institute conducted the study while utilizing two drugs that would, in theory, be able to control the actions associated with glioblastoma. Keep in mind that a similar study was done in the past, focusing on one pathway, but the results that came about was not successful. With this method, though, two cell signaling pathways have been given focus. This is an improvement, to be certain, but I feel as though there should be focus given on a genetic abnormality that is common in around one-third of glioblastoma patients.

The report talked about the loss of a gene referred to as PTEN. For those who are unaware, PTEN acts as a tumor-suppressing gene. If the PTEN gene is not seen, though, the body is met with a chain reaction that can cause overactive molecular growth signals which, in turn, can cause cells to grow at malignant rates until the activity eventually reaches the brain. With these drugs brought into effect, the gene in question is not replaced but rather the growth caused is blocked.

With this in mind, it is important to make note of all of the occurrences that can be seen in the human body. Not all of them are going to make sense but it's apparent that they work together in order to create order. When a single element is out of place, though, the risk for contracting a condition can increase; this was proven by the potential lack of the PTEN gene. With certain drugs coming together and then going on to become implemented, though, the research focused on brain tumors can be given more essential information.




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